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Lung Injury in COVID-19—An Emerging Hypothesis

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Lung injury with COVID-19 may be due to a complex underlying pathophysiology. Cytokine release syndrome appears to be a catalyst of different inflammatory pathways promoting lung parenchymal injury and thromboembolic… Click to show full abstract

Lung injury with COVID-19 may be due to a complex underlying pathophysiology. Cytokine release syndrome appears to be a catalyst of different inflammatory pathways promoting lung parenchymal injury and thromboembolic phenomena (“dual hit” injury). Recently, severe neurological manifestations such as acute disseminated encephalomyelitis, which may be not linked to lung pathology, have been identified in COVID-19, contributing thus further to the versatility of its clinical features.

Keywords: covid emerging; injury covid; injury; lung injury; lung

Journal Title: ACS Chemical Neuroscience
Year Published: 2020

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