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Polymer Microarrays for the Discovery and Optimization of Robust Optical-Fiber-Based pH Sensors.

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Polymer microarrays were utilized for the high-throughput screening and discovery of optimal polymeric substrates capable of trapping functional ratiometric fluorescence-based pH sensors. This led to the identification of poly(methyl methacrylate-… Click to show full abstract

Polymer microarrays were utilized for the high-throughput screening and discovery of optimal polymeric substrates capable of trapping functional ratiometric fluorescence-based pH sensors. This led to the identification of poly(methyl methacrylate- co-2-(dimethylamino) ethyl acrylate) (PA101), which allowed, via dip coating, the attachment of fluorescent pH sensors onto the tips of optical fibers, resulting in robust, rapid, and reproducible sensing of physiological pHs.

Keywords: optimization robust; based sensors; polymer microarrays; robust optical; microarrays discovery; discovery optimization

Journal Title: ACS combinatorial science
Year Published: 2019

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