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Here we present a “thinking-outside-the-box”, tunable nanoplatform for oral delivery of proteins using insulin as a model protein. These nanosystems offer noncompetitive active transport exploiting transferrin receptors present in the… Click to show full abstract
Here we present a “thinking-outside-the-box”, tunable nanoplatform for oral delivery of proteins using insulin as a model protein. These nanosystems offer noncompetitive active transport exploiting transferrin receptors present in the intestine and permit tailored release in vivo. Such delivery approaches have the potential to individualize insulin therapy to a regimen that is compatible with the patient’s glucose profile.
Keywords:
tunable nanoplatform;
oral delivery;
delivery proteins;
delivery;
active transport;
noncompetitive active
Journal Title: ACS Macro Letters
Year Published: 2017
Link to full text (if available)
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Journal Title: ACS Macro Letters
Year Published: 2017
Link to full text (if available)
Share on Social Media: Sign Up to like & get
recommendations!