This highlight describes novel substituted pyrido-[4,3-d]-pyrimidine compounds as KRAS (Kirsten rat sarcoma viral oncogene homologue) inhibitors. The invention provides details about novel pyrido-[4,3-d]-pyrimidine compounds, their pharmaceutical composition, potential use, and… Click to show full abstract
This highlight describes novel substituted pyrido-[4,3-d]-pyrimidine compounds as KRAS (Kirsten rat sarcoma viral oncogene homologue) inhibitors. The invention provides details about novel pyrido-[4,3-d]-pyrimidine compounds, their pharmaceutical composition, potential use, and treatment for KRAS-related diseases, such as various cancers.
Keywords:
novel pyrido;
compounds kras;
kras inhibitors;
pyrido pyrimidine;
pyrimidine compounds
Journal Title: ACS medicinal chemistry letters
Year Published: 2025
Link to full text (if available)
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Journal Title: ACS medicinal chemistry letters
Year Published: 2025
Link to full text (if available)
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recommendations!