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An electrochemical synthesis for quinazolines and quinazolinones was developed via a C(sp3)-H amination/C-N cleavage by virtue of the anodic oxidation. The reaction can be carried out in aqueous media under… Click to show full abstract
An electrochemical synthesis for quinazolines and quinazolinones was developed via a C(sp3)-H amination/C-N cleavage by virtue of the anodic oxidation. The reaction can be carried out in aqueous media under mild conditions to afford the desired products with high yields. The reaction mechanism was proposed after detailed investigation.
Keywords:
sp3 amination;
amination cleavage;
oxidation;
quinazolines quinazolinones
Journal Title: ACS Omega
Year Published: 2020
Link to full text (if available)
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Journal Title: ACS Omega
Year Published: 2020
Link to full text (if available)
Share on Social Media: Sign Up to like & get
recommendations!