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Selective Synthesis of Bis-Heterocycles via Mono- and Di-Selenylation of Pyrazoles and Other Heteroarenes

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The insertion of selenium was achieved in the form of mono-selenides and di-selenides for the preparation of novel bis-heterocyclic compounds. This method is more general and provides scaffold diversity with… Click to show full abstract

The insertion of selenium was achieved in the form of mono-selenides and di-selenides for the preparation of novel bis-heterocyclic compounds. This method is more general and provides scaffold diversity with high yields of products. The concentration-dependent mono- and di-selenylation reaction selectivity was achieved using SeO2 as an efficient selenylating reagent.

Keywords: heterocycles via; bis heterocycles; selective synthesis; selenylation; mono selenylation; synthesis bis

Journal Title: ACS Omega
Year Published: 2022

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