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An efficient and novel photoinduced trifluoromethylation employing CF3Br as a trifluoromethyl source is described. With commercially accessible fac-Ir(III)(ppy)3 as the catalyst, radical trifluoromethylation between O-silyl enol ether and CF3Br occurs… Click to show full abstract
An efficient and novel photoinduced trifluoromethylation employing CF3Br as a trifluoromethyl source is described. With commercially accessible fac-Ir(III)(ppy)3 as the catalyst, radical trifluoromethylation between O-silyl enol ether and CF3Br occurs successfully. This method provides various α-CF3-substituted ketones with a broad substrate scope in good yields under mild reaction conditions.
Keywords:
substituted ketones;
trifluoromethyl source;
cf3 substituted;
cf3br trifluoromethyl;
photoinduced trifluoromethylation;
trifluoromethylation
Journal Title: ACS Omega
Year Published: 2022
Link to full text (if available)
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Journal Title: ACS Omega
Year Published: 2022
Link to full text (if available)
Share on Social Media: Sign Up to like & get
recommendations!