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An efficient [4 + 1] annulation reaction between in situ generated azoalkene intermediates and α-bromocarbonyls has been established. A series of skeletally diverse aza-heterocycles with a functionalized quaternary center were… Click to show full abstract
An efficient [4 + 1] annulation reaction between in situ generated azoalkene intermediates and α-bromocarbonyls has been established. A series of skeletally diverse aza-heterocycles with a functionalized quaternary center were obtained in up to 89% yield under mild conditions.
Keywords:
synthesis aza;
annulation;
center;
chemodivergent synthesis;
aza heterocycles
Journal Title: ACS Omega
Year Published: 2022
Link to full text (if available)
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Journal Title: ACS Omega
Year Published: 2022
Link to full text (if available)
Share on Social Media: Sign Up to like & get
recommendations!