Photo by 12tones from unsplash
Pseudo-ternary mixtures of lamellar phase phospholipids (DPPC and brain sphingomyelin with cholesterol) were studied below Tm, while comparing the influence of cholesterol content, temperature and the presence of small quantities… Click to show full abstract
Pseudo-ternary mixtures of lamellar phase phospholipids (DPPC and brain sphingomyelin with cholesterol) were studied below Tm, while comparing the influence of cholesterol content, temperature and the presence of small quantities of Vitamin D binding protein (DBP) or Vitamin D receptor (VDR). The measurements, conducted by X-ray diffraction (XRD) and nuclear magnetic resonance (NMR), cover a range of cholesterol concentrations (20% mol. wt to 40% mol. wt.) and physiologically relevant temperature range (294 K – 314 K). In addition to rich intra-phase behaviour, data and modelling are used to approximate the lipids’ headgroup location variations under the above-mentioned experimental conditions.
Journal Title: ACS Omega
Year Published: 2022
Link to full text (if available)
Share on Social Media: Sign Up to like & get
recommendations!