Photo by itfeelslikefilm from unsplash
Efficient O-alkylation of phenols and carboxylic acids has essential applications in organic synthesis. A mild alkylation method for phenolic and carboxylic OH groups is developed using alkyl halides as alkylation… Click to show full abstract
Efficient O-alkylation of phenols and carboxylic acids has essential applications in organic synthesis. A mild alkylation method for phenolic and carboxylic OH groups is developed using alkyl halides as alkylation reagents and tetrabutylammonium hydroxide as a base, and lignin monomers can be fully methylated in quantitative yields. Additionally, phenolic and carboxylic OH groups can be alkylated by different alkyl halides in one pot in different solvent systems.
Keywords:
organic synthesis;
lignin monomers;
tetrabutylammonium hydroxide;
applications organic
Journal Title: ACS Omega
Year Published: 2023
Link to full text (if available)
Share on Social Media: Sign Up to like & get
recommendations!
Journal Title: ACS Omega
Year Published: 2023
Link to full text (if available)
Share on Social Media: Sign Up to like & get
recommendations!