LAUSR

Magnetic hyperthermia is an emerging technique used for the treatment of tumors, where the infected cells will be deactivated using the heat generated from magnetic particles. This study discusses the viability of yttrium iron garnet (YIG) in magnetic hyperthermia treatment. YIG is synthesized using hybrid microwave-assisted hydrothermal and sol–gel auto combustion techniques. The formation of the garnet phase is confirmed using powder X-ray diffraction studies. Further, the morphology and grain size of the material are analyzed and estimated with the help of field emission scanning electron microscopy. Transmittance and optical band gap are obtained using UV–visible spectroscopy. Raman scattering of the material is discussed to understand the phase and vibrational modes. The functional groups of garnet are studied using Fourier transform infrared spectroscopy. Further, the effect of the synthesizing routes on the characteristics of the materials is discussed. A relatively higher magnetic saturation value is observed in the hysteresis loop at room temperature of YIG samples, which is synthesized by a sol–gel auto combustion technique, and it confirms the ferromagnetic behavior. The colloidal stability and surface charge of the prepared YIG are evaluated by a zeta potential measurement. In addition, magnetic induction heating studies are carried out for both prepared samples. The specific absorption rates of 1 mg/mL concentration are 237 and 214 W/g at 35.33 kA/m and 316 kHz field of sol–gel auto combustion and hydrothermal methods, respectively. Due to their higher saturation magnetization of 26.39 emu/g, the sol–gel auto combustion method produced effective YIG and demonstrated superior heating efficiency than the hydrothermally prepared sample. The prepared YIG are biocompatible, and their hyperthermia properties may be explored in various biomedical applications.