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Metal-Free Vinyl C–H Sulfenylation/Alkyl Thiolation of Ketene Dithioacetals for the Synthesis of Polythiolated Alkenes

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The sulfenylation of the vinyl C–H bond in ketene dithioacetals leading to the synthesis of polythiolated alkenes is achieved via the promotion of molecular iodine. In addition, alkyl thiols also… Click to show full abstract

The sulfenylation of the vinyl C–H bond in ketene dithioacetals leading to the synthesis of polythiolated alkenes is achieved via the promotion of molecular iodine. In addition, alkyl thiols also exhibit tolerance to the C–H bond elaboration reaction for the synthesis of corresponding alkylthiolated ketene dithioacetals.

Keywords: ketene dithioacetals; sulfenylation; synthesis polythiolated; synthesis; polythiolated alkenes

Journal Title: ACS Omega
Year Published: 2018

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