The pancreas is a complex glandular organ in the abdominal cavity of humans. Pancreatic tissues contain different function regions that participate in different biological processes. Moreover, pancreatic cells can be… Click to show full abstract
The pancreas is a complex glandular organ in the abdominal cavity of humans. Pancreatic tissues contain different function regions that participate in different biological processes. Moreover, pancreatic cells can be clustered into different types according to their location regions. Cells in different types are involved in different biological functions as either endocrine or digestive. In this study, we investigated the gene expression of pancreatic cells in six types, tried to identify differentially expressed genes among different cell types, and obtained pancreatic cell biomarkers. In detail, the Monte Carlo feature selection (MCFS) method was performed on the dataset consisting of the gene expression of 2282 pancreatic cells. The resulting feature list was further used in the incremental feature selection method, with the help of a support vector machine to extract important differentially expressed genes. In addition, on the basis of the 776 informative features yielded by the MCFS method, we set u...
               
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