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Probing the Role of Imidazopyridine and Imidazophosphorine Scaffolds To Design Novel Proton Pump Inhibitor for H+,K+-ATPase: A DFT Study

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Clinically used proton pump inhibitors (PPIs) are not perfectly suitable for prolonged acid suppression because of the short plasma half-lives of 1–1.5 h. However, tenatoprazole, an imidazopyridine... Click to show full abstract

Clinically used proton pump inhibitors (PPIs) are not perfectly suitable for prolonged acid suppression because of the short plasma half-lives of 1–1.5 h. However, tenatoprazole, an imidazopyridine...

Keywords: proton pump; probing role; role imidazopyridine; proton

Journal Title: ACS Omega
Year Published: 2019

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