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An operationally simple, efficient, and metal-/peroxide-free three-component reaction of alkynes, iodine, and sodium sulfinates has been developed for the construction of highly functionalized tetrasubstituted alkenes. Iodo- and sulfonyl-containing tetrasubstituted alkenes,… Click to show full abstract
An operationally simple, efficient, and metal-/peroxide-free three-component reaction of alkynes, iodine, and sodium sulfinates has been developed for the construction of highly functionalized tetrasubstituted alkenes. Iodo- and sulfonyl-containing tetrasubstituted alkenes, such as vinyl ketones, allylic alcohols, and conjugated enynes, could be obtained regio- and stereoselectively in up to 96% yield.
Keywords:
tetrasubstituted alkenes;
iodine sodium;
reaction alkynes;
alkynes iodine;
three component;
component reaction
Journal Title: ACS Omega
Year Published: 2018
Link to full text (if available)
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Journal Title: ACS Omega
Year Published: 2018
Link to full text (if available)
Share on Social Media: Sign Up to like & get
recommendations!