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Mitochondria-Targeted New Blue Light-Emitting Fluorescent Molecular Probe

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Discovery of a nontoxic fluorescent molecular probe to “light up” specific cellular organelles is extremely essential to understand dynamics of intracellular components. Here, we report a new nontoxic mitochondria-targeted linear… Click to show full abstract

Discovery of a nontoxic fluorescent molecular probe to “light up” specific cellular organelles is extremely essential to understand dynamics of intracellular components. Here, we report a new nontoxic mitochondria-targeted linear bithiazole compound, containing trifluoroacetyl terminal groups, which emits intense blue fluorescence and stained mitochondria of various cells. Interestingly, the power of fluorescence is completely off when the bithiazole unit is stapled by a carbonyl bridge.

Keywords: mitochondria targeted; fluorescent molecular; targeted new; light; molecular probe

Journal Title: ACS Omega
Year Published: 2019

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