An interesting synthetic transformation of protection–deprotection chemistry in an isatin molecule is achieved. Morita–Baylis–Hillman (MBH) adduct formation used as protection of the C-3 position in the isatin molecule is reported.… Click to show full abstract
An interesting synthetic transformation of protection–deprotection chemistry in an isatin molecule is achieved. Morita–Baylis–Hillman (MBH) adduct formation used as protection of the C-3 position in the isatin molecule is reported. C–C bond cleavage in the MBH adduct of isatin with the help of phenylhydrazine and C=N bond cleavage in the phenylhydrazone derivative of isatin with the help of K10 clay are studied systematically and reported as deprotection.
Keywords:
protection deprotection;
chemistry;
mbh adduct
Journal Title: ACS Omega
Year Published: 2019
Link to full text (if available)
Share on Social Media: Sign Up to like & get
recommendations!
Journal Title: ACS Omega
Year Published: 2019
Link to full text (if available)
Share on Social Media: Sign Up to like & get
recommendations!