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A novel, metal catalyst-free, and efficient method has been developed for the synthesis of (pyrazol-4-ylidene)pyridine derivatives. The process involves dehydrogenative coupling of 1-amino-2-imino-pyridines with 1-aryl-5-pyrazolone derivatives utilizing O2 as the… Click to show full abstract
A novel, metal catalyst-free, and efficient method has been developed for the synthesis of (pyrazol-4-ylidene)pyridine derivatives. The process involves dehydrogenative coupling of 1-amino-2-imino-pyridines with 1-aryl-5-pyrazolone derivatives utilizing O2 as the sole oxidant. The new method benefits from a high atom economy, efficiency, and substrate scope, as well as the simplicity of reaction and product purification procedures.
Keywords:
pyridines aryl;
imino pyridines;
metal catalyst;
amino imino;
catalyst free;
pyrazol ylidene
Journal Title: ACS Omega
Year Published: 2019
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Journal Title: ACS Omega
Year Published: 2019
Link to full text (if available)
Share on Social Media: Sign Up to like & get
recommendations!