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Deoxygenation of Ethers To Form Carbon-Carbon Bonds via Nickel Catalysis.

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In this article a successful protocol was developed to construct carbon-carbon bonds by the extrusion of the O atom of ethers via nickel catalysis in the presence of reductants. This… Click to show full abstract

In this article a successful protocol was developed to construct carbon-carbon bonds by the extrusion of the O atom of ethers via nickel catalysis in the presence of reductants. This methodology is featured as a highly economic route to construct sp3-sp3 C-C bonds through dual C-O activation of ethers with good functional group tolerance.

Keywords: carbon bonds; nickel catalysis; carbon; carbon carbon; via nickel

Journal Title: Journal of the American Chemical Society
Year Published: 2017

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