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Ex Vivo Tracking of Endogenous CO with a Ruthenium(II) Complex.

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A two-photon fluorescent probe based on a ruthenium(II) vinyl complex is capable of selectively detecting carbon monoxide in cells and ex vivo using mice with a subcutaneous air pouch as… Click to show full abstract

A two-photon fluorescent probe based on a ruthenium(II) vinyl complex is capable of selectively detecting carbon monoxide in cells and ex vivo using mice with a subcutaneous air pouch as a model for inflammation. This probe combines highly selective and sensitive ex vivo detection of endogenous CO in a realistic model with facile, inexpensive synthesis, and displays many advantages over the widely used palladium-based systems.

Keywords: ruthenium; vivo; vivo tracking; endogenous ruthenium; tracking endogenous; ruthenium complex

Journal Title: Journal of the American Chemical Society
Year Published: 2017

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