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Nickel-Catalyzed Stereoselective Diarylation of Alkenylarenes.

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A three-component coupling of aryl bromides, arylboron reagents, and alkenylarenes is presented. The method tolerates a variety of substitution patterns on all of the components. In particular, 1,2-disubstituted alkenylarenes are… Click to show full abstract

A three-component coupling of aryl bromides, arylboron reagents, and alkenylarenes is presented. The method tolerates a variety of substitution patterns on all of the components. In particular, 1,2-disubstituted alkenylarenes are suitable and undergo highly diastereoselective diarylation.

Keywords: stereoselective diarylation; catalyzed stereoselective; diarylation; diarylation alkenylarenes; nickel catalyzed

Journal Title: Journal of the American Chemical Society
Year Published: 2018

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