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A Mild and Direct Site-Selective sp2 C-H Silylation of (Poly)Azines.

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A base-mediated protocol that allows for the site-selective sp2 C-H silylation of azines is described. This method is distinguished by its mild conditions, simplicity and excellent site-selective modulation for a… Click to show full abstract

A base-mediated protocol that allows for the site-selective sp2 C-H silylation of azines is described. This method is distinguished by its mild conditions, simplicity and excellent site-selective modulation for a diverse set of azines, even in the context of late-stage functionalization, while exhibiting orthogonal reactivity with classical silylation reactions.

Keywords: site selective; site; sp2 silylation; selective sp2

Journal Title: Journal of the American Chemical Society
Year Published: 2019

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