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Designer chimeric antigen receptor (CAR) T cells (dTc) have come to be the latest designer ‘drug’ for treatment of cancer. This technology has generated multiple apparent cures in the treatment… Click to show full abstract
Designer chimeric antigen receptor (CAR) T cells (dTc) have come to be the latest designer ‘drug’ for treatment of cancer. This technology has generated multiple apparent cures in the treatment of B-cell malignancies, but has had much less impact in solid tumors. This perspective article considers the prior experience and the future possibilities for extending this technology’s potential to the much more numerous solid tumors for a broader clinical utility.
Keywords:
designer;
designer car;
solid tumor;
tumor designer;
challenges solid;
car
Journal Title: Cancer Gene Therapy
Year Published: 2017
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Journal Title: Cancer Gene Therapy
Year Published: 2017
Link to full text (if available)
Share on Social Media: Sign Up to like & get
recommendations!