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tsRNAs: new players in mammalian retrotransposon control

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A recent study led by Professor Rob Martienssen in Cell showed that 3′-tRNA-derived small RNAs can suppress long terminal repeat retrotransposon activity in mammalian cells by mechanisms independent of DNA-associated… Click to show full abstract

A recent study led by Professor Rob Martienssen in Cell showed that 3′-tRNA-derived small RNAs can suppress long terminal repeat retrotransposon activity in mammalian cells by mechanisms independent of DNA-associated epigenetic marks, suggesting how the genome may defend itself from retrotransposon invasion during epigenetic reprogramming.

Keywords: tsrnas new; retrotransposon control; players mammalian; mammalian retrotransposon; new players; retrotransposon

Journal Title: Cell Research
Year Published: 2017

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