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Blood flow forces liver growth

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Increases in biomechanical forces in the liver’s blood vessels have now been shown to activate two mechanosensitive proteins. The proteins trigger blood-vessel cells to deploy regenerative factors that drive liver… Click to show full abstract

Increases in biomechanical forces in the liver’s blood vessels have now been shown to activate two mechanosensitive proteins. The proteins trigger blood-vessel cells to deploy regenerative factors that drive liver growth.Mechanical forces on endothelial cells promote hepatocyte proliferation.

Keywords: blood flow; liver growth; flow forces; forces liver

Journal Title: Nature
Year Published: 2018

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