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Chromatin modified in a molecular reaction chamber

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Chromatin, the complex of DNA and protein in cell nuclei, can be modified by ubiquitin molecules. It emerges that this modification occurs in a molecular reaction chamber formed from an… Click to show full abstract

Chromatin, the complex of DNA and protein in cell nuclei, can be modified by ubiquitin molecules. It emerges that this modification occurs in a molecular reaction chamber formed from an enzyme and a scaffold protein. A phase-separated reaction chamber for chromatin ubiquitination.

Keywords: reaction chamber; chromatin; chamber chromatin; molecular reaction

Journal Title: Nature
Year Published: 2020

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