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T cells engineered to target senescence

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Senescence is a hallmark of cellular ageing and contributes to many diseases. A new method enabling immune cells to target senescent cells might offer improved therapeutic options. CAR T cells… Click to show full abstract

Senescence is a hallmark of cellular ageing and contributes to many diseases. A new method enabling immune cells to target senescent cells might offer improved therapeutic options. CAR T cells that target senescent cells combat disease in mouse models.

Keywords: target senescence; cells engineered; senescence; engineered target

Journal Title: Nature
Year Published: 2020

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