LAUSR

outcomes. A recent meta-analysis of randomised clinical trials of intentional weight loss and mortality identified two in populations with diabetes/pre-diabetes. Both demonstrated no harm associated with the weight loss arm, each with a protective but non-significant effect. If we wish to understand the role of weight, gain, maintenance and loss on future survival in those populations living with an obesity-related disease, all medical journals should call for studies designed to address this question. And reject future studies on the obesity paradox that fall into the collider bias trap.