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The molecular pathogenesis of the NUP98-HOXA9 fusion protein in acute myeloid leukemia

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diagnosis, time from diagnosis to transplant and disease status at transplant. VRD has become the most common pretransplant induction regimen after 2010. Only, half of patients are placed on post-transplant… Click to show full abstract

diagnosis, time from diagnosis to transplant and disease status at transplant. VRD has become the most common pretransplant induction regimen after 2010. Only, half of patients are placed on post-transplant treatment at day 100 after AHCT, with lenalidomide as the most frequently used agent. Counterintuitively, we did not see an increase in the use of maintenance treatment in the most recent period. Despite these impressive gains in the field, progression of MM remains the most frequent cause of death.

Keywords: leukemia molecular; pathogenesis nup98; molecular pathogenesis; nup98 hoxa9; hoxa9 fusion; leukemia

Journal Title: Leukemia
Year Published: 2017

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