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US 9,676,836 Methods and compositions to identify and characterize new channelrhodopsins derived from algae and several of which are red-shifted. The rhodopsin domain of these red-shifted channelrhodopsins can be cloned… Click to show full abstract
US 9,676,836 Methods and compositions to identify and characterize new channelrhodopsins derived from algae and several of which are red-shifted. The rhodopsin domain of these red-shifted channelrhodopsins can be cloned and expressed in mammalian systems and used in optogenetic applications and as therapeutic agents. Also, methods and compositions for use in red-shifting the absorbance maxima of channelrhodopsins in order to improve their utility for use in vivo. Board of Regents of the University of Texas System (Austin, TX, USA) Spudich JL, Govorunova EG, Sineshchekov OA 6/13/2017
Journal Title: Nature Biotechnology
Year Published: 2017
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