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A CRISPR screen conducted in a CD4+ T cell leukemia line has identified host factors required for HIV infection but dispensable for cellular survival. The results highlight sulfation on the… Click to show full abstract
A CRISPR screen conducted in a CD4+ T cell leukemia line has identified host factors required for HIV infection but dispensable for cellular survival. The results highlight sulfation on the HIV co-receptor CCR5 and cellular aggregation as potential targets for therapeutic intervention.
Keywords:
host targets;
targets hiv;
finding host;
hiv therapy;
host
Journal Title: Nature Genetics
Year Published: 2017
Link to full text (if available)
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Journal Title: Nature Genetics
Year Published: 2017
Link to full text (if available)
Share on Social Media: Sign Up to like & get
recommendations!