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Divergent evolutionary trajectories in transplanted tumor models

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Human-derived tumor models are becoming popular in the context of personalized medicine, but a new study shows that these models could be less representative of primary tumors than previously thought,… Click to show full abstract

Human-derived tumor models are becoming popular in the context of personalized medicine, but a new study shows that these models could be less representative of primary tumors than previously thought, particularly when using late passages.

Keywords: trajectories transplanted; tumor models; evolutionary trajectories; transplanted tumor; divergent evolutionary; tumor

Journal Title: Nature Genetics
Year Published: 2017

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