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Urothelial cancer in 2017: Changes in expectations for metastatic urothelial carcinoma

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2017 saw the publication of clinical trial data and the approval of new treatment approaches for metastatic urothelial carcinoma. Pembrolizumab is now a well-established treatment for patients with disease progression… Click to show full abstract

2017 saw the publication of clinical trial data and the approval of new treatment approaches for metastatic urothelial carcinoma. Pembrolizumab is now a well-established treatment for patients with disease progression after cisplatin, with high-level evidence supporting its superiority over second-line chemotherapy. For patients ineligible for cisplatin, atezolizumab and pembrolizumab provide meaningful clinical benefit as frontline therapies.

Keywords: urothelial cancer; cancer 2017; urothelial carcinoma; 2017 changes; metastatic urothelial

Journal Title: Nature Reviews Clinical Oncology
Year Published: 2018

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