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Loss of β-cell mass is posited to occur gradually over a long period of time in preclinical type 1 diabetes mellitus, as the first signs of β-cell autoimmunity generally emerge… Click to show full abstract
Loss of β-cell mass is posited to occur gradually over a long period of time in preclinical type 1 diabetes mellitus, as the first signs of β-cell autoimmunity generally emerge several years before clinical presentation. This concept has recently been challenged by observations of acute loss of β-cell mass in late-phase preclinical disease.
Keywords:
presentation;
cell;
cell mass;
loss cell
Journal Title: Nature Reviews Endocrinology
Year Published: 2017
Link to full text (if available)
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Journal Title: Nature Reviews Endocrinology
Year Published: 2017
Link to full text (if available)
Share on Social Media: Sign Up to like & get
recommendations!