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Bone: Bone marrow adipocytes in 3D

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Culturing bone marrow stromal cells on 3D silk scaffolds supports their proliferation and adipogenesis, while minimizing the activation of inflammatory pathways. Therefore, differentiation of bone marrow adipocytes in 3D culture… Click to show full abstract

Culturing bone marrow stromal cells on 3D silk scaffolds supports their proliferation and adipogenesis, while minimizing the activation of inflammatory pathways. Therefore, differentiation of bone marrow adipocytes in 3D culture might provide a more representative model for the study of bone marrow adipose tissue than is offered by traditional 2D cell cultures.

Keywords: bone; bone bone; marrow adipocytes; bone marrow

Journal Title: Nature Reviews Endocrinology
Year Published: 2018

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