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Diabetic nephropathy: Renoprotective effects of GLP1R agonists and SGLT2 inhibitors

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New data from the LEADER trial show that the glucagon-like peptide 1 receptor agonist liraglutide protects against diabetic nephropathy in patients with type 2 diabetes mellitus. The renoprotective efficacy of… Click to show full abstract

New data from the LEADER trial show that the glucagon-like peptide 1 receptor agonist liraglutide protects against diabetic nephropathy in patients with type 2 diabetes mellitus. The renoprotective efficacy of liraglutide is not, however, as great as that reported for the sodium-glucose cotransporter 2 inhibitor emplagiflozin in the EMPA-REG OUTCOME trial.

Keywords: nephropathy renoprotective; renoprotective effects; glp1r agonists; effects glp1r; diabetic nephropathy; agonists sglt2

Journal Title: Nature Reviews Nephrology
Year Published: 2017

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