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Acute kidney injury: Targeting Treg cells to protect the kidney

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Despite the increased mortality risk of recipients of diabetic versus nondiabetic deceased donor kidneys, for many transplant candidates, accepting a diabetic donor kidney confers a survival benefit compared with remaining… Click to show full abstract

Despite the increased mortality risk of recipients of diabetic versus nondiabetic deceased donor kidneys, for many transplant candidates, accepting a diabetic donor kidney confers a survival benefit compared with remaining on the waitlist, say researchers. The greatest survival benefit of diabetic donor kidney transplantation compared with remaining on the waitlist was seen for diabetic recipients at centres with long waitlist times, whereas candidates aged <40 years showed no survival benefit of accepting a diabetic donor kidney.

Keywords: kidney injury; survival benefit; donor kidney; acute kidney; diabetic donor; kidney

Journal Title: Nature Reviews Nephrology
Year Published: 2017

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