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Regenerative medicine: Breaking Prometheus's curse for cartilage regeneration

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Like the mythical eagle devouring Prometheus's liver as fast as it regrew, chronic inflammation hinders cartilage regeneration in inflammatory arthritis. Using stem cells engineered to secrete anti-inflammatory molecules in response… Click to show full abstract

Like the mythical eagle devouring Prometheus's liver as fast as it regrew, chronic inflammation hinders cartilage regeneration in inflammatory arthritis. Using stem cells engineered to secrete anti-inflammatory molecules in response to local inflammatory factors could provide a way to keep the eagle at bay as the stem cells differentiate into chondrocytes.

Keywords: medicine; breaking prometheus; cartilage regeneration; medicine breaking; regenerative medicine

Journal Title: Nature Reviews Rheumatology
Year Published: 2017

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