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Evaluation of microsatellite instability (MSI) of every colorectal cancer (CRC) is important for prognostic and therapeutic purposes, while molecular testing helps identify actionable targeted therapy for patients with metastatic disease.… Click to show full abstract
Evaluation of microsatellite instability (MSI) of every colorectal cancer (CRC) is important for prognostic and therapeutic purposes, while molecular testing helps identify actionable targeted therapy for patients with metastatic disease. This review will discuss the biomarkers commonly encountered in the clinical evaluation of CRC, and practical issues regarding MSI screening, reporting, interpretation, molecular test indication, and specimen requirements.
Keywords:
biomarkers evaluation;
evaluation colorectal;
colorectal cancer;
cancer;
practical guide;
guide biomarkers
Journal Title: Modern Pathology
Year Published: 2019
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Journal Title: Modern Pathology
Year Published: 2019
Link to full text (if available)
Share on Social Media: Sign Up to like & get
recommendations!