Fig. 1 Stylized artistic images of forebrain neurons derived from iPSCs of antidepressant (SSRI) resistant depressed patients. Neurons from SSRI-resistant patients display differential activity in response to serotonin, downstream of… Click to show full abstract
Fig. 1 Stylized artistic images of forebrain neurons derived from iPSCs of antidepressant (SSRI) resistant depressed patients. Neurons from SSRI-resistant patients display differential activity in response to serotonin, downstream of key excitatory serotonergic receptors, highlighting a potential mechanism underlying SSRI-resistance in major depressive disorder (MDD). Images are modified from Figure 2c of Vadodaria et al., on pages 795–807 of this issue
               
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