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close surveillance, continued vigilance with social distancing and masks, and aggressive management in case of infection. In conclusion, our study demonstrates that administration of a third mRNA vaccine dose yields… Click to show full abstract
close surveillance, continued vigilance with social distancing and masks, and aggressive management in case of infection. In conclusion, our study demonstrates that administration of a third mRNA vaccine dose yields a signi fi cant increase in anti-S RBD antibodies and neutralization capacity in HCT recipients. Older age, allo-HCT and IST are major determinants of low humoral immunogenicity to SARS-CoV-2 vaccination. More studies are needed to fi nd the threshold of clinical ef fi cacy of anti-S RBD titers and rates of viral neutralization especially in the setting of new variants and antigenic shift.
Journal Title: Bone Marrow Transplantation
Year Published: 2022
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