LAUSR

https://doi.org/10.1038/s41415-020-1786-1 30 and 60 seconds treatment exposure under both clean and dirty conditions. In contrast, when PVP-I was tested at 1:2 dilution a >4 log10 kill at 15 seconds and >5 log10 kill at 30 and 60 seconds in comparison to control was seen in both clean and dirty. Dental practice poses a potential risk of COVID-19 cross-infection among patients, dentists and their assistants through direct exposure to saliva and indirect contact through contaminated instruments.3 Several associations, including the Australian Dental Association, have recommended using a preprocedural mouthwash with products such as povidone iodine.4 In our study, we present direct evidence of the virucidal activity of PVP-I gargle and against SARS-CoV-2 in just 15 seconds. In today’s scenario, PVP-I gargle and mouthwash could be an adjuvant to PPEs in reducing the risk of COVID-19 transmission in healthcare practices, especially when oral interventions are warranted, such as in dental practice. P. Hassandarvish, V. Tiong, A. B. Sazaly, Malaya, Malaysia; N. A. Mohamed, Kuala Lumpur, Malaysia; H. Arumugam, A. Ananthanarayanan, M. Qasuri, M. Hadjiat, Singapore