Some cancer predisposing germline mutations cause overt birth defects and congenital anomalies. Others are clinically silent and can only be suspected by the presence of increased cancer incidence in family… Click to show full abstract
Some cancer predisposing germline mutations cause overt birth defects and congenital anomalies. Others are clinically silent and can only be suspected by the presence of increased cancer incidence in family members. A new study shows that long-term monitoring of families may be needed to discover previously unsuspected underlying cancer predisposing mutations.
               
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