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Intrinsic factors that regulate dormancy of disseminated tumour cells (DTCs) are predominantly unknown. Now, knockdown of MSK1 is shown to accelerate bone metastasis of luminal breast cancer cells. MSK1 acts… Click to show full abstract
Intrinsic factors that regulate dormancy of disseminated tumour cells (DTCs) are predominantly unknown. Now, knockdown of MSK1 is shown to accelerate bone metastasis of luminal breast cancer cells. MSK1 acts through epigenetic mechanisms that enforce the luminal phenotype and promote steady-state maintenance of DTCs within bone.
Keywords:
role tumour;
dormancy;
msk1 role;
biology;
tumour dormancy;
illuminating msk1
Journal Title: Nature Cell Biology
Year Published: 2018
Link to full text (if available)
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Journal Title: Nature Cell Biology
Year Published: 2018
Link to full text (if available)
Share on Social Media: Sign Up to like & get
recommendations!