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A coordinated DNA damage response mediated by p53 to repair DNA lesions or to promote apoptosis is essential for maintenance of genome stability. A study now unveils the long non-coding… Click to show full abstract
A coordinated DNA damage response mediated by p53 to repair DNA lesions or to promote apoptosis is essential for maintenance of genome stability. A study now unveils the long non-coding RNA GUARDIN as a component of this pathway, which protects genome integrity in a pleiotropic fashion.
Keywords:
integrity;
biology;
genome integrity;
guarding genome;
lncrna guarding
Journal Title: Nature Cell Biology
Year Published: 2018
Link to full text (if available)
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Journal Title: Nature Cell Biology
Year Published: 2018
Link to full text (if available)
Share on Social Media: Sign Up to like & get
recommendations!