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It is commonly accepted that disseminated tumour cells survive cytotoxic chemotherapy because they are not proliferating. A new study now finds that, in contrast to this long-standing concept, both dormant… Click to show full abstract
It is commonly accepted that disseminated tumour cells survive cytotoxic chemotherapy because they are not proliferating. A new study now finds that, in contrast to this long-standing concept, both dormant and proliferative cancer cells can be protected from chemotherapy when they reside at the perivascular niche.
Keywords:
cellular dormancy;
resistance beyond;
biology;
beyond cellular;
therapy resistance
Journal Title: Nature Cell Biology
Year Published: 2019
Link to full text (if available)
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Journal Title: Nature Cell Biology
Year Published: 2019
Link to full text (if available)
Share on Social Media: Sign Up to like & get
recommendations!