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Dynamics of mRNA entry into stress granules

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Stressed eukaryotic cells store mRNAs in protein-rich condensates called stress granules. Using single-molecule tracking techniques to examine how mRNAs enter stress granules, a new study shows that mRNAs make transient… Click to show full abstract

Stressed eukaryotic cells store mRNAs in protein-rich condensates called stress granules. Using single-molecule tracking techniques to examine how mRNAs enter stress granules, a new study shows that mRNAs make transient contacts with the granule surface before stable association, and become largely immobile after entry.

Keywords: stress granules; entry stress; mrna entry; stress; dynamics mrna

Journal Title: Nature Cell Biology
Year Published: 2019

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