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Fixed-dose combination therapy and polypills to prevent and treat CVD

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In the QUARTET trial, initial treatment with a single pill containing quarter doses of four antihypertensive drugs achieved and maintained a greater blood-pressure-lowering effect than initial monotherapy with full-dose irbesartan. Click to show full abstract

In the QUARTET trial, initial treatment with a single pill containing quarter doses of four antihypertensive drugs achieved and maintained a greater blood-pressure-lowering effect than initial monotherapy with full-dose irbesartan.

Keywords: therapy polypills; dose combination; polypills prevent; fixed dose; combination therapy; prevent treat

Journal Title: Nature Reviews Cardiology
Year Published: 2021

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