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Validation of plasma-derived small extracellular vesicles as cancer biomarkers

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A role for extracellular vesicles and particles (EVPs) as cancer biomarkers has been elusive. A mass spectrometry-based comparative analysis of EVPs from individuals with or without cancer has now enabled… Click to show full abstract

A role for extracellular vesicles and particles (EVPs) as cancer biomarkers has been elusive. A mass spectrometry-based comparative analysis of EVPs from individuals with or without cancer has now enabled the identification of tumour-associated protein profiles in EVPs in plasma and paired tumour tissues, validating the role of EVPs as a novel liquid biopsy approach in cancer diagnosis.

Keywords: extracellular vesicles; validation plasma; cancer; cancer biomarkers; plasma derived

Journal Title: Nature Reviews Clinical Oncology
Year Published: 2020

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