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Immunotherapy biomarkers: the long and winding road

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A recent meta-analysis examined and validated biomarkers of response to immune-checkpoint inhibitors (ICIs). Herein, we discuss the findings of this analysis, which are consistent with previously identified determinants of ICI… Click to show full abstract

A recent meta-analysis examined and validated biomarkers of response to immune-checkpoint inhibitors (ICIs). Herein, we discuss the findings of this analysis, which are consistent with previously identified determinants of ICI efficacy and demonstrate that some genetic variables influence response across multiple cancer types.

Keywords: immunotherapy biomarkers; long winding; oncology; winding road; biomarkers long

Journal Title: Nature Reviews Clinical Oncology
Year Published: 2021

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